Functional Dynamics of Hemostasis and Hemorheology in Young Men at Risk of Arterial Hypertension
Maria A. Vinichenko1, Svetlana Yu. Zavalishina2* and Galina S. Mal3

1Department of the Russian language, professional speech and intercultural communication, Belgorod State National Research University ((NRU " BelSU")), 308007, Belgorod, Russia

2Faculty of Medicine, Russian State Social University, 129226, Moscow, Russia

3Department of Pharmacology, Kursk State Medical University, 305041, Kursk, Russia

Corresponding Author E-mail: svetlanazsyu@mail.ru

Abstract: Of great medical and social importance in modern conditions is the increase in the effectiveness of preventing the development of arterial hypertension at a young age. Purpose of the work: to evaluate the impact of systematic dosed jogging on the parameters of the homeostasis system and the rheological properties of blood in adolescents with a predisposition to the development of arterial hypertension. The study included 60 young men with high normal blood pressure and the risk of developing arterial hypertension with normal body weight. They were divided into 2 groups. The first of them (31 people) began regular jogging for 1 hour a day, 6 times a week for 1 year. The second group (29 young men) kept their previous inactive way of life. The work took into account the level of blood pressure, the amount of fibrinogen in the blood, plasminogen activity, the amount of soluble fibrin-monomer complexes, activated partial thromboplastin time, international normalized ratio, platelet aggregation, blood viscosity. Student's t-test was calculated. As a result of regular jogging in young men with a predisposition to the formation of arterial hypertension, it was possible to normalize the level of blood pressure, homeostasis parameters and hemorheology parameters taken into account. The changes achieved had a very positive effect on microcirculation, providing a general recovery. Long-term low physical activity in young men at risk of developing arterial hypertension contributed to the preservation of elevated blood pressure numbers, aggravation of homeostasis disorders and deterioration of blood rheology.

Keywords: Adolescence; Arterial hypertension; Blood rheology; Hemostasis; Muscle activity; Physical training

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