Eco-Friendly Low Concentration Silver Nanoparticles Acquiring Cotton Textile Antifungal Activities for Pulmonary Aspergillosis Protection
Fayez K. Fouda1
, Ahmed Saad Montaser2, Gehan T. El-Bassyouni3, Esmat M.A. Hamzawy4, Eman Refaat Youness5* and Mohamed S. Abd El-Aziz61Medical Biochemistry Department, Medical Research and clinical studies Institute,National Research Centre, Doki, Giza, Egypt
2Textile Research Institute, National Research Centre, Cairo, Giza, Egypt.
3Refractories, Ceramics and Building Materials Dept., National Research Centre, Dokki, Cairo, Egypt.
4Glass Research Department., National Research Centre, Dokki, Cairo, Egypt.
5Medical Biochemistry Department,Medical Research and clinical studies Institute, National Research Centre, Doki, Giza, Egypt
6Genetic Engineering and Biotechnology Institute, Microbial Chemistry Department, National Research Centre (NRC), Dokki, Egypt
Corresponding Author E-mail: hoctober2000@yahoo.com
Abstract: Aspergillosis is a fungal infection cause reduction or suppression of innate immune system. Occasionally silver nanoparticles showed antibacterial activity rather than anti-fungal activity. In the current paper three different shapes and concentrations of silver nanoparticles (AgNPs) were synthesized using dextrin and starch, then applied to cotton for acquiring antifungal properties. TEM illustrates the size, shape and homogeneity of the AgNPs. Atomic absorption spectroscopy (AAS) quantified the AgNPs in the colloidal solution. Attenuated total reflection ATR/FT-IR spectroscopy and scanning electron microscope (SEM) coupled with Energy Dispersive X-Ray Analysis (EDX) to screen the homogeneity and dispersion of the AgNPs. Different shapes (rode and triangular) of AgNPs (10-17nm) were produced using 10~5 ppm of the AgNPs. Antifungal activity towards Aspergillus Niger fungus was documented using the disc diffusion method. Cotton treated with AgNPs showed significant effective antifungal properties at lower concentrations (~10 ppm) preserving its white color compared to the higher concentrations (>100 ppm)of the AgNPs. Manufactured cotton fabrics treated with low concentrations of AgNPs were examined towards the recognition of the antifungal properties with minimal industrial footprint which may expose a novelpossibility for antifungal applications.
Keywords: Anti-Fungal; Aspergillosis; Cotton, Textile; Silver Nanoparticles; Tissue Resist Fungus Back to TOC