Pharmacotherapy of Distal Autonomic Sensory Polyneuropathies in Vibration Disease
E. Yu. Radoustskaya, Ya. I. Onischuk and I. I. NovikovaFederal Budgetary Scientific Institution "Novosibirsk Research Institute of Hygiene" of Rospotrebnadzor, Novosibirsk, Russian Federation
Corresponding Author E-mail: aizman.roman@yandex.ru
Abstract: The article is devoted to the current medical and social problem - vibration disease, which takes an important place in the clinic of occupational pathology. The syndromological classification of the vibration disease of the last revision is given here. Particular attention is paid to the pharmacotherapy of neuropathic manifestations of the disease. The article presents the data of the performed clinical studies of Cokarnit and alpha-lipoic acid preparations efficiency in patients with professional vegetative-sensory polyneuropathy of limbs. Clinical efficacy of Cocarnit with a possibility of using Cocarnit as monotherapy as well as complex therapy (Cocarnit and lipoic acid) in neuropathic pain syndrome associated with peripheral polyneuropathy of professional genesis was determined.
Keywords: Alpha-Lipoic Acid Preparations; Cocarnitis; Electromyography; M-Response Amplitude; Occupational polyneuropathy; Peripheral Nerve Impulse Velocity; Vibration Disease Back to TOC