Early Intubation Reduces the Risk of Death Among COVID-19 Patients: An Observational Study
Abhilash Dash
, Cherian Roy, Biswajit Nayak and Shakti Bedanta Mishra*Department of Critical Care Medicine, IMS and SUM Hospital, Siksha O Anusandhan (Deemed to be) University, K-8, Kalinga Nagar, Bhubaneswar, Odisha, India.
Corresponding Author E-mail: shaktimishra84@gmail.com
Abstract: Background: The objective of this study was to find the association of invasive mechanical ventilation, non-invasive mechanical ventilation (N.I.V) and high flow nasal canula (HFNC) with mortality in COVID 19 pneumonia patients with ARDS. This is an observational cohort study conducted among patients those who were infected with COVID19 infection and received ventilator support. Materials and Methods: This study was a single centred, conducted among COVID19 patients, who came to a tertiary hospital in Bhubaneswar, Odisha. All patients admitted with COVID19 infection and received mechanical ventilation in between August 2020 to November 2020 was included in this study. As this is an observational cohort study, any intervention not required. Only, data collectors collected all relevant patient data using an android-based data collection platform. Result: 398 patients were found to be eligible for this study. Among them, only 24.47% patients received invasive mechanical ventilation and rest were on N.I.V (62.77%) and HFNC support (12.77%). 26 patients died among the 92 invasively ventilated patients, whereas the mortality rate among N.I.V group of patients (78.7%) was significantly higher. Increased TLC count, C-Reactive, Protein, Urea, Creatinine, Heart rate, Respiratory rate were mostly associated with increased mortality among non-invasively ventilated patients. Conclusion: Early intubation may decrease the risk of mortality in patients infected with severe COVID19 infection.
Keywords: COVID19 Mortality; High Flow Nasal Cannula (HFNC) oxygen therapy; Invasive mechanical ventilation; N.I.V Back to TOC