Review on Pharmacology of Atropine, Clinical Use and Toxicity
Sara A. Aldossary
Department of pharmaceutical sciences, college of clinical pharmacy, king faisal university,31982 alahsa, Saudi Arabia.
Corresponding Author E-mail: saldossary@kfu.edu.sa
Abstract: Extracts of the deadly nightshade plant, Atropa belladonna, contain a naturally occurring amine, Atropine, which is isolated from Atropa belladonna and other nightshade plants (Solanaceae). The plants are used for making a wide range of drugs. Drug absorption via the mucosal membrane of the stomach is extremely low because the acid gastric contents. Atropine is a prescription pharmaceutical used to treat the symptoms of decreased heart rate (bradycardia). Atropine is also used to suppress salivation and bronchial secretions before to surgery. Atropine can be used on its own or in combination with other drugs. Anticholinergic, Antispasmodic Agents are the class of medications that include Atropine. Toxic side effects include ventricular fibrillation (VF), as well as hypotension (hyperventilation), convulsions (delirium), hallucinations (delirium), convulsions (delirium), delirium (delirium), and excitation (excitation) in the elderly. Except in levels often used for preanesthetic treatment, atropine is generally contraindicated in individuals with glaucoma, pyloric stenosis, or prostatic hypertrophy. In this review the history and pharmacolog of atropine will be discussed in details. In addition to medical uses of this drug and contraindications.
Keywords: Atropine; Therapeutic; Toxicity; Uses Back to TOC