Preparation, Diagnosis and Evaluation of Cyclic-Tryptophan Derivatives as Anti Breast Cancer Agents
Nagham Mahmood Aljamali1*
and Sabrean Farhan Jawad21Department of Chemistry ,Synthetic Organic Chemistry ,Iraq.
2Department of Pharmacy, Al-Mustaqbal University College, Babylon, Iraq.
Corresponding Author E-mail: dr.nagham_mj@yahoo.com
Abstract: The importance of research lies in the treatment of cancerous tumors due to the spread of cancerous tumors in recent decades, so researchers have to insist on finding alternative and more treatments safe from chemotherapy and radiation, which are derivatives of some amino acids, which we attended in our current research. Also, some research showed that taking tryptophan for 3 days before exercise can improve energy and efficiency during exercise, but other preliminary research shows that taking tryptophan during exercise does not improve endurance during cycling exercises. For a few days before exercise to notice any benefit. In this research, we prepared derivatives of cyclic tryptophan and studied their efficacy as anti-tumors, and they gave good results in reducing the size of cancerous tumors and reducing their spread in the body., then sympathy all synthesized new cyclic-tryptophan compounds by numerous techniques (FT.IR ,H.NMR)–spectrophotometric, other physical and chemical properties ,with studying for one of new prepared derivatives as anti breast cancer.
Keywords: Anti Breast; Anticancer; Heterocyclic; Tryptophan; Triazole Back to TOC