Evaluation of Radiation Doses and Estimation of the Risk of Radiation-Induced carcinogenesis in Women Undergoing Screening Mammography Examinations
Zakaria Tahiri1*
, Mounir Mkimel2, Laila Jroundi3 and Fatima Zahra Laamrani31Doctoral Study Center for Life and Health Sciences, Faculty of Medicine and Pharmacy of Rabat, Impasse Souissi, Rabat 10100, Morocco.
2Laboratory of Technology and Health Sciences, High Institute of Health Sciences, Route de Casablanca km 3,5 université hassan 1er. BP 555, Settat, Morocco.
3Emergency Radiology Department, Faculty of Medicine and Pharmacy of Rabat, Impasse Souissi, Rabat 10100, Morocco.
Corresponding Author E-mail: tahiri.zakaria@gmail.com
Abstract: Digital Mammography is used as a screening tool to discover breast cancer at an early stage, the benefits and harms of this techniques is under scrutiny hence and Moroccan regulations governing radiation protection of patients have been strengthened, the need to investigate the dose received during screening mammography and the risk associated. This study is consisted of examining 126 mammography projections, for 63 women. All examinations were performed with a full digital mammography machine, technical and exposure parameters were recorded, statistical analysis was carried out using Microsoft Excel in order to calculate local DRLs and compare them with international standards. Cancer risk has been estimated using BEIR VII report methods. The mean glandular dose MGD was 1,09±0, 45 mGy and 1,26±0,74 mGy for craniocaudal (CC) and mediolateral oblique (MLO) respectively, DRLs were 1,34 for CC view and 1,36 for MLO view. Of the 100,000 women exposed, Lifetime Attributable Risk of cancer incidence has been found to be 0,76 for CC examination, 0.88 for MLO, and 1,64 for the full mammography protocol. Established local DRLs in this study are lower compared to that of United Kingdom and France and higher compared to that of Nigeria and Australia. A potential risk of radiation-induced carcinogenesis exists, and there is a need for optimization of screening mammography practices.
Keywords: Breast Cancer; Mammography; Radiation Biological Effects; Radiation Protection Back to TOC