Assessment of Liver Enzymes Levelamong Obesesudanese Individuals in Khartoum State-Sudan
Elyasa Elfaki1
, Alneil Hamza2*, Malak Ahmed3, Mariam Ibrahim4, Ezedine KAbdalhabib2 and Trig Karar51Department of Clinical Laboratory Sciences, College of Applied Medical Sciences,Jouf University, Qurayyat,77423.
2Department of Clinical Laboratory Sciences, Jouf University, Qurayyat,77423.
3Department of Clinical Chemistry, College of Medical Laboratory Sciences, Elrazi University ,Khartoum,79371.
4Department of Clinical Chemistry, College of Medical Laboratory Sciences, Sudan University of Science and Technology ,Khartoum,79371
5Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh ,11543
Corresponding Author E-mail: aahamza@ju.edu.sa
Abstract:
Introduction: Overweight and obesity prevalence continues to increase and worldwide growing epidemic health problems. Obesity imposes a significant effect on liver functions that may be associated with a substantial risk factor for the development of several non-communicable diseases, considerable disability, and premature death.
Objective: To estimate and compare serum activity of ALT, ALP, and GGT among healthy and obese Sudanese individuals. Materials and methods: a total number of 80 participants were enrolled in this cross-sectional study, and they were categorized into 40 obese and 40 normal-weight individuals. Serum liver enzyme activity was measured for each participant.Results: A significant increase was found in ALT, ALP, and GGT levels among the obese group. There is a statistical difference of GGT level mean between gender within the obese group. A positive correlation was observed between the BMI and serum level of ALT (r=0.343, p =0.002), ALP (r=0.503, p <0.001) and GGT (r=0.237, p= 0.034) and positive correlation between obesity duration and GGT level (r=0.461, p =0.003).Conclusion: Study results revealed that obesity was associated with a substantial elevation in liver enzymes that considered risk factors for liver diseases in Sudanese individuals.
Keywords: Liver Diseases; Liver Enzymes; Obesity; Sudanese Individuals Back to TOC