Traumatic Spinal Cord Injury; Theranostic Applications of Advanced MRI Techniques
Daryoush Fatehi1, Farhad Naleini2, Mohammad Gharib Salehi2, Daryoush Afshari3, Sam Mirfendereski4, Mohammad Farzizadeh2 and Ayoob Rostamzadeh5*1Department of Medical Physics, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran 2Department of Radiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. 3Department of Neurology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. 4Department of Radiology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran. 5Department of Anatomy and Neuroscience, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
Abstract: Imaging technology is an important part of the diagnosis and management of spinal trauma. However, many efforts have been made to develop new diagnostic biomarkers through advanced imaging techniques. Unfortunately, there is still no consensus for practical use of biomarkers in SCI patients The authors conducted an all-encompassing literature review and relevant images were included as examples. Spinal cord and soft-tissue injuries are best evaluated by magnetic resonance imaging (MRI). However, advanced MRI techniques provide researchers with a non-invasive approach that allows evaluation of physiological and biochemical condition of the spinal cord and the brain at cellular and molecular level. The advent of new rehabilitation and treatment strategies could demand more precise and advanced techniques to approach the pathophysiology and anatomy of the spinal cord, offering more accurate and non-invasive support to research and clinical follow up.
Keywords: Spinal trauma; Imaging techniques; Magnetic resonance imaging; Spinal cord injury; Imaging biomarker Back to TOC