An Unusual Case of Human Intravenous Immunoglobulin Induced Erythema Multiforme in a Child.

Kamalakshi G. Bhat¹, Amrita Parida^2*, Ashwin Kamath² and Rashmi R. Rao²

¹Department of Paediatrics, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka 575001. India.

²Department of Pharmacology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka 575001. India.

Corresponding Author E-mail: amrita_parida@yahoo.com

Abstract:

Human intravenous immunoglobulin (IVIG) is used for diverse conditions is a relatively safe drug with fewer adverse effects. Here, we report a rare case of IVIG-induced erythema multiforme in a four-year-old female child. The child tolerated the initial doses of IVIG well; however, following the fifth dose, she developed multiple erythematous rash over the trunk, upper and lower limbs associated with itching. She was diagnosed to have IVIG-induced erythema multiforme and treated symptomatically and recovered completely within a week. There is limited literature available related to IVIG-induced erythema multiforme; hence we decided to report this case.

Keywords: Adverse Drug Reaction; Erythema Multiforme; Human IVIG

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