Anti-inflammatory Activity of Wheatgrass Juice in Albino Rats
G. K. Nalini1, Venkatesh M. Patil2, S. Ramabhimaiah3, Prabhakar Patil2 and V. Vijayanath4¹Department of Pharmacology, Hassan Institute of Medical sciences, HASSAN, Karnataka India.
2,3 Department of Pharmacology, Navodaya Medical College, Raichur, Karnataka India.
4Department of Forensic Medicine and Toxicology, S. S. Institute of Medical Sciences and Research Centre Davangere, Karnataka India.
Abstract: To study the anti-inflammatory effect of wheatgrass juice in albino rats. Anti-inflammatory activity of wheatgrass juice was evaluated by using carrageenin-induced rat hind paw edema model for acute study, rexin pellet-induced granuloma in rat model and formalin-induced rat hind paw edema model for chronic study. The results obtained were compared with diclofenac Sodium, standard drug and control. Wheatgrass produced significant anti-inflammatory effect in chronic models. In rexin pellet model, the effect of wheatgrass was more than diclofenac sodium. In formalin-induced rat hind paw edema model, the effect of wheat grass was less than diclofenac sodium. However, the wheatgrass juice showed no significant anti-inflammatory activity in acute models. Wheatgrass juice exhibits anti-inflammatory activity in chronic inflammation.
Keywords: Wheatgrass juice; anti-inflammatory effect; paw edema; granuloma; diclofenac Back to TOC