Copper and Zinc Quotient in Haemoglobinopathies
C. B. S. Dangi¹, Manpreet Kaur¹ and Madhulika Singh*2¹Human Genetic Laboratory, C.S.R.D, People’s Group, Bhopal India.
2Sadhu Vaswani P.G. College, Bairagarh, Bhopal India.
Abstract: The plasma copper (Cu) and zinc (Zn) levels act as measure in a various haemoglobinopathies. The role of copper and zinc deficiency in various haemoglobinopathies remains poorly defined. Growth retardation and impaired immune function, suggest a relationship between haemoglobinopathies and level of copper and zinc. Fluctuations in the essential elements levels seem to be related to the different complications associated with the disease. In most of the Haemoglobinopathies there is sever hemolysis of red blood cells that results in release of zinc from red blood cells to blood and then excreted in urine leads to zinc deficiency. Hypercupremia occurs in acute and chronic infections and hemochromatosis, which is a principal complication of haemoglobinopathies.. The zinc supplementation may be helpful in reducing the sufferings of complication in patients of haemoglobinopathies
Keywords: Copper; Haemoglobinopathies; Zinc; Thalasseamia Back to TOC