Investigating the Effects of Thymus Vulgaris Products and Clotrimazole Lotion to Prevent the Growth of Candida Albicans Fungus
Elahe Jahan1*, Masumeh Amiridelui2, Mahsa Sharifi Nodehi3, Atefeh Haghighat41Jahan Elahe, Msc of Nursing, Nurse – Midwifery Department, Semnan branch , Islamic Azad University, Semnan, Iran. 2Amiridelui Masumeh,MSc,Educational Member Department of Community and Mental Health,School of Nursing and Midwifery,Social Development and Health Promotion Research Center,School of Nursing and Midwifery,Gonabad University of Medical Sciences,Gonabad,Iran 3Sharifi nodehi Mahsa , Msc of Nursing, Nurse – Midwifery Department, Semnan branch , Islamic Azad University, Semnan, Iran. 4Haghighat Atefeh, Msc of Nursing, Nurse – Midwifery Department, Semnan branch , Islamic Azad University, Semnan, Iran.
Abstract: Since a long time, medicinal plants have been used for treatment of diseases, especially infectious diseases. Plant species diversity and the tendency of society to use the natural materials in the treatment of diseases have placed the screening of essences and herbal extracts in the core attention of researchers. The aim of this study was to evaluate the effect of Thymus vulgaris extract and essence on Candida albicans and compare its effects with clotrimazole lotion. Ethanolic, methanolic, and aqueous extracts of Thymus vulgaris prepared by maceration extraction method. Thymus vulgaris extract was prepared by water distillation. Then, they were used in research. Thymus vulgaris essence prepared from Baryj Essence Company. Then paper discs which coated with herbal compounds placed in Candida albicans medium and their zone diameters of growth inhibition compared with that of clotrimazole ointment. the essence and (ethanolic, methanolic) extracts and distilled extract of Thymus vulgaris have antifungal effects and its essence zone diameter of growth inhibition was higher than its extracts zone diameter of growth inhibition. This study shows the good effects of Thymus vulgaris essence and (ethanolic, methanolic) extracts and distilled extract in preventing Candida albicans pathogenic fungi growth. It was also found that Thymus vulgaris is more effective in preventing Candida albicans pathogenic fungi than clotrimazole lotion .Therefore; It can be used as a substitute for clotrimazole lotion in treatment of candidiasis.
Keywords: Thymus vulgaris; Clotrimazole; Candida albicans Back to TOC