Correlation of Total Testosterone and Sex Hormone Binding Globuline Level with Abdominal Obesity in Male Population of Legian Village, Kuta, Bali, Indonesia
I. Made Pande Dwipayana1,2, Arini Junita1, Siswadi Semadi1, Ketut Suastika1, Made Ratna Saraswati1, Wira Gotera1 and Anak Agung Gede Budhiarta11Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University, Bali, Indonesia.
2Doctoral Program, Faculty of Medicine, Udayana University, Bali, Indonesia.
Corresponding Author E-mail: dwipayanapande@yahoo.com
Abstract: Abdominal obesity is a part of metabolic syndrome. There are several causes of abdominal obesity and one of which is hormonal factor. Decrease of testosterone level has been thought as one of many possible cause of abdominal obesity in men, but the exact mechanism has not been well elaborated until now. The aim of this study was to evaluate the correlation of total testosterone and SHBG levels with abdominal obesity in Legian village, Kuta, Bali, Indonesia. An analytic cross sectional study has been conducted. The samples were selected from healthy men population in Legian village, with the total number of 80 subjects. Among 80 samples, the lowest total testosterone level is 1.38 nmol/L, and sex hormone – binding globulin (SHBG) is 1.53 nmol/L. The highest total testosterone level is 32.44 nmol/L and SHBG level 75.43 nmol/L. The means of total testosterone and SHBG levels were 16.60 nmol/L and 30.03 nmol/L respectively. We found significant negative correlation between abdominal obesity with testosterone levels (r=-0.233, p=0.037), but there were no significant correlation between sex hormone binding globuline levels with abdominal obesity (r=-0.042, p=0.720). This finding support the hypothesis that lower testosterone level maybe responsible for abdominal obesity in men.
Keywords: Abdominal Obesity SHBG; Total Testosterone; Back to TOC