Comparative Anthelmintic Activity of Different Extracts of Portulaca Oleraceae L.Whole Plant

Trupti P. Durgawale¹, Chitra C. Khanwelkar², Pratik P. Durgawale³ and Satish V. Kakade⁴

¹Department of Pharmacology, Krishna Institute of Medical Sciences Deemed University (KIMSDU), Karad, Maharashtra, India.

²Department of Pharmacology, Krishna Institute of Medical Sciences Deemed University (KIMSDU), Karad, Maharashtra, India.

³Genetic and Molecular Laboratory, Krishna Institute of Medical Sciences Deemed University (KIMSDU), Karad, Maharashtra, India.

⁴Department of Community Medicine, Krishna Institute of Medical Sciences Deemed University (KIMSDU), Karad, Maharashtra, India.

Corresponding Author E-mail: truptipdurgawale@gmail.com

Abstract: Parasitic diseases, especially, helmenthiasis pose a threat to human health and livestock alike. This imposes a greater burden of health care expenditure in tropical countries where these are endemic. Recently, the research for naturally- derived anthelmintics has been encouraged. Portulaca olarecea, commonly called as Purslane, has been part of diet in Asian and Mediterranean region. In the present study, various extracts of Purslane were tested for their anthelmintic activity on Indian adult earthworms (Pheretima posthuma). The anthelmintic activity of all the extracts was concentration- dependent and comparable to that of standard; while aqueous extract exhibited greatest activity. Further in- vivo tests and phytochemical research would shed light on potential activities of Purslane.

Keywords:  Anthelmintic; Portulaca Olarecea;Pheretima posthuma

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