Comparing the Effects of Adding Fentanyl vs Ketamine to 1/5% Lidocaine in Para-cervical Block in Order to Reduce of Post-operative Pain Among the Patients Applying for Curettage
Alireza Kamali1 , Fateme Seidi2 , Maryam Shokrpour2* and Mehri Jamilian21Department of Anesthesiology, Arak University of Medical Sciences, Arak Iran.
2Department of Gynecology, Arak University of Medical Sciences, Arak, Iran.
Corresponding Author Email: Maryam_shokrpour@yahoo.com
Abstract: Curettage is a common procedure in gynecology. In order to sedate and reduce postoperative pain, different analgesic techniques have been proposed. The objective of this study was to compare the level of sedation and postoperative pain in patients submitted to curettage, using Ketamine vs Fentanyl to lidocaine for para-cervical block. In this double blind clinical trial study, 120 eligible women candidated for curettage were enrolled. The subjects were divided to three equal groups. In first group, 5ml lidocaine 1.5% plus 1ml Fentanyl, in the second group 5ml lidocaine 1.5% plus 1 ml Ketamine, and in third group 5ml lidocaine 1.5% plus 1cc normal saline as placebo was administrated for para-cervical block. The postoperative pain was evaluated within 0-30 and 60 minutes after operation via visual analogue scale (VAS), time of analgesic request in 24hours were recorded. The VAS score within 0 and 30 minutes after procedure was lower in Ketamine and Fentanyl groups than placebo (p<0.05), but in 60 min was lower in ketamine than fentanyl (p<0.05). The time of analgesic request was longer in ketamine group (p<0.05). Ketamine and Fentanyl are effective for improving post-operative pain, but Ketamine is more effective.
Keywords: Curettage; Ketamine; Fentanyl; Post-operative Pain Back to TOC