Manuscript accepted on :27 Seep 2019
Published online on: 30-09-2019
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1525Evelyn Sharon S* and V. Chitra
Department of Pharmacology, SRM College of Pharmacy, SRM IST
Corresponding Author’s E-mail: evelynsharonsukumar@gmail.com
DOI : https://dx.doi.org/10.13005/bpj/1787
Abstract
Osteoporosis is a metabolic bone disorder which causes bone loss in course of time leading to increasing in the fracture risk. The disease is often silent and known only when fractures occur. Both men and women are equally affected. But women are more susceptible to osteoporosis. The main cause of fragility fractures in women is due to the estrogen deficiency. For the treatment of Osteoporosis the potential biological use of traditional medicines have been exposed to logical assessment since synthetic medications are considered to have a wide range of side effects and they lack efficacy. Hence broad research is to be done to examine the therapeutic plants to be utilized as an option for the treatment of Osteoporosis. The present survey work demonstrates the data on medicinal plants with their common name, phytochemical constituents, reported pharmacological activities and their Osteoporotic action.
Keywords
Osteoporosis; Medicinal Plants; Estrogen Replacement Therapy; Phytochemical Constituents; Postmenopausal
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| Copy the following to cite this article: Sharon S. E, Chitra V. Medicinal Plants for the Treatment of Postmenopausal Osteoporosis. Biomed Pharmacol J 2019;12(3). |
| Copy the following to cite this URL: Sharon S. E, Chitra V. Medicinal Plants for the Treatment of Postmenopausal Osteoporosis. Biomed Pharmacol J 2019;12(3). Available from: https://bit.ly/2oKkGSw |
Introduction
Osteoporosis is a major public health problem globally. It is characterized as a skeletal disorder due to decreased bone strength prompting an expanded danger of fractures (The Royal Australian College of General Practitioners and Osteoporosis Australia., 2017). Osteoporosis literally means “porous bones” and is characterized by decreased mineral density of the bones. It is frequently seen in aging population and is considered as a modern day epidemic. Osteoporosis makes the bones weak and fragile increasing the chances of getting them fractured with trivial trauma. Such a kind of fractures may lead to pain, deformity and disability (The Royal Australian College of General Practitioners and Osteoporosis Australia., 2017). Osteoporosis and related fractures are the major noteworthy reason for morbidity and mortality of the elderly population. From the age of 50the remaining lifetime risk of fractures is evaluated to be 50% in women and 30% in men(Nguyen, Ahlborg, Eisman, & Nguyen, 2007).According to WHO “Osteoporosis is a disease characterized by low bone mass and micro architectural destruction of the bone tissue leading to fragility and sequential increase in fracture risk resulting in fractures with minimal trauma”. (Soelaiman, Das, Shuid, Mo, & Mohamed, 2013).
Osteoporosis has risen as one of the leading health issue worldwide. It is often considered as silent since it is known only when it causes bone fracture(Res, 2013). Due to increased longevity of life in the Indian population Osteoporosis has become the major cause of morbidity and mortality when compared to the western countries (National & Journal, 1996).The predominance of Osteoporosis increases with age in women and not in men. It was reported that 22% of the population will have Osteoporosis by 2025 and 33% in 2050 (Mithal%2
