Risk Factor in Patients of Cerebrovascular Accident
Ranjit Patil¹ and Uplabdhi Raghuwanshi²¹Medical Biochemistry Department, Dr. Ulhas Patil Medical College, Jalgaon India. ²Maharashtra University of Health Sciences, Nashik B.J. Medical College, Pune, India. Corresponding Author e-mail:uplabdhir@yahoo.com
Abstract: The present study aims at-(1) The effect of derangement of lipid patterns in CVA patients; and (2) The effect of CVA on derangement of lipid patterns; both on 1st and 7th day. The study included 25 patients of CVA (stroke) whose 12 -14 hr fasting samples were obtained, within 24 hours of admission, i.e. on 1st and 7th day. The measured lipid levels (TC, HDL-c, & RF [TC: HDL-c]) were compared to the normal range (130 to 250 mgs/dL, 30 to 70 mgs/dL, & < 4:1, respectively). It was found that measured mean value of serum TC was 190.24 mgs/dL, HDL-c = 38.68 mgs/dL, & RF = 5: 1, with corresponding normal values on 1st day, which on 7th day showed decrease for 158.16 mgs/dL, 35.68 mgs/dL, & 4.5: 1 correspondingly. The measured lipid parameters showed a considerable decrease on 7th day, as the stroke severity decreased, it could be proportionally linked with the severity of stroke. Thus stroke causes a significant derangement in lipids. Individuals with low HDL-c should be considered a group at high risk of stroke, whereas direct relationship has been observed with levels of TC & RF (comparing 1st day with control).
Keywords: Cerebrovascular Accident; Total Cholesterol; High-density lipoprotein cholesterol; Risk factor Back to TOC