The Effects of Air Pollution on The Salivary Iga Levels in Children
Solmaz Pourzare Mehrbani1, Zohreh Babaloo2, Hosein Eslami1, Tahmoores Abdollahian3 and Vahid motameni tabatabai4

1Assistant Professor ,Department of Oral and maxillofacial Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

2Assistant Professor, Department of Immunology, Tabriz University of Medical Sciences, Tabriz, Iran.

3Assistant Professor, Department of Oral and maxillofacial Medicine, Tabriz University of Medical Science, Tabriz, Iran.

4Under graduated student, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Corresponding Author E-mail: Tahmoores2009@yahoo.com

Abstract: The effects of air pollution on the human health and morbidity and mortality are well demonstrated. Air pollution affects immune system and may have effect on immunoglobulins. In this study we aim to evaluated the effects of air pollution on the salivary IgA levels in children. In this descriptive study, 44 children from Tabriz industrial city (polluted city) and 44 children from Kaleibar city (a Tabriz suburban area) with similar socioeconomic status were selected. Saliva samples were taken and salivary IgA levels were compared between groups. All statistical tests were performed using SPSS for windows Version 21. Independent t test was used to compare quantitative data between groups(P-Value=0.001). The mean levels of the salivary IgA in Tabriz city was significantly lower than was significantly lower than Kaleibar (9.73±1.57 vs. 12.25±4.4 mg/dl, p=0.001). Similar to the literature, we observed that that the salivary IgA levels are decreased in areas with air pollutions.

Keywords: Air pollution; Saliva; Immunoglobulin A

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