Evaluation of Oxidative Stress and Other Biochemical Markers in Female Subjects Suffering from Chronic Renal Failure and Chronic Renal Failure with Hypertension
Drutpal Singh Baghel, Meena Verma, Sangeeta Paneri and Saroj Mawase

Department of Medical Biochemistry, M. G. M. Medical College, Indore (India).

Abstract: The current study was performed in the Department of Medical Biochemistry, M. G. M. Medical College, Indore (M.P.) to asses the trend of antioxidatnts and some important biochemical markers in female subjects suffering from chronic renal failure and chronic renal failure with hypertension. The blood samples were analyzed for sodium, potassium, protein, creatinine, urea, superoxide dismutase, glutathione reductase, glutathione peroxidase, catalase, and malondialdehyde. Highly singnificant (P<0.001) increased results were observed in case of serum postassium ions, creatinine, urea and plasma malondialdehyde. Serum sodium ions, protein, superoxide dismutase and haemolysate glutathione reductase, glutathione peroxidase and catalase were decreased highly significantly (p<0.001) in chronic renal failure and chronic renal failure with hypertension groups when compared with age matched female healthy control group.

Keywords: Chronic Renal Failure; Hypertension

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