Effect of Endotracheal Suctioning with and without Normal Saline on Hemodynamic and Respiratory Parameters in Patients Undergoing Mechanical Ventilation in ICU of Hospitals Supervised by Guilan University of Medical Sciences
Masoomeh Adib1, Atefeh Ghanbari1*, Cyrus Emir Alavi2 and Ehsan Kazemnezhad Leyli3

1Social Determinants of Health Research Center (SDHRC), Guilan University of Medical Science, Rasht . IR Iran.

2Anesthesiologist, Vascular Surgery and Dialysis research Center, Guilan University of Medical Science, Rasht . IR Iran

3Biostatistic, Social Determinants of Health Research Center (SDHRC), Guilan University of Medical Science, Rasht . IR Iran.

Abstract: Airway suction is one of the most popular methods for drainage airways in patients with artificial airway; thus, correct suction of airways is important. Hence, the purpose of this study is to determine the effects of suction methods with and without normal saline on hemodynamic and respiratory patients. This randomized crossover clinical trial was conducted on two groups consisting of 37 mechanically ventilated patients by suctioning with and without normal saline. After at least 2 hours, the second stage was conducted and the patients were displaced in groups A and B. respiratory and hemodynamic parameters were measured at different intervals. The average age of patients was 21.8 ± 51.2; in terms of consciousness, 70% of patients were Sedate. Systolic blood pressure (P = 0.20), diastolic blood pressure (P <0.0001), average arterial pressure (P <0.0001) and heart rate (P <0.0001) increased over time immediately after the suction and then declined; in approximately 5 minutes after suction, it approached its baseline. This difference was significant in other cases except for systolic blood pressure. The mean respiratory rate, mean airway pressure, mean oxygen-saturated haemoglobin, mean end-tidal carbon dioxide were similar in both suction groups with and without normal saline during different time steps and no significant differences were observed. As long as there is no sufficient evidence to use normal saline on endotracheal suctioning, this method is not recommended to be used routinely. It is recommended to substitute strategies such as airway hydration, adequate hydration of patients, early mobilization of patients and administration of mucolytic drugs.

Keywords: Endotracheal suction; normal saline; intensive care units; hemodynamics; respiration

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