Functional Features of Platelet Secretion in Piglets During Early Ontogenesis
E. S. Tkacheva1,2 and S. Y. U. Zavalishina3

1Federal State Budgetary Educational Institution for Higher Professional training "Vologda State Dairy Farming Academy named after N.V. Vereshchagin", st. Schmidt, 2, Vologda, 160555-Russia.

2All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals, Institute of village, Borovsk, 249013-Russia.

3Russian State Social University, st. V. Pika, 4, Moscow, 129226-Russia.

Corresponding Author E-mail: svetlanazsyu@mail.ru

Abstract: Physiologically, the secretion is considered to be a very important element of the platelet hemostasis system. Its functional state seriously determines the activity of primary hemostasis and microcirculation parameters in the capillaries, and, consequently, the course of metabolic processes throughout the body. It is known that the success of the entire hemostasis, as well as the activity of the processes in the development of the vessels of the body of productive animals, depends on the level of secretory activity of platelets. Of particular physiological significance are its features during early ontogenesis, when the body grows, matures and reaches its optimum productive qualities. For this reason, additional study of the secretory potential of platelets during the first year of life is of great importance for the physiology of the blood of piglets. These studies can help in finding approaches to the continuation of further intensification of pig production. In the work carried out, it was found that the ability of platelets to secrete increases in piglets during early ontogenesis. The main mechanism of this process should be considered as an increase in platelets of basal amount and self-assembly of actin and myosin. These changes are amplified at the physiological level in piglets due to the increase in the content of adenosine phosphate in platelet granules and the severity of its secretion under the influence of aggregation inducers. The increased activity of platelet secretion in piglets during the first year of life contributes to maintaining their microcirculation processes in the tissues at the level of their body's needs for nutrients and oxygen.

Keywords: Adhesion; Aggregation; Early Ontogenesis; Piglets; Platelets; Secretion

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