Phytochemical Analysis and Anti-Inflammatory Activity of Pisonia Grandis R.Br.
R. Radha1*, S. Arokiyaraj2, P. Agastian2, K. Balaraju2, R. Mohan Kumar3 and P. Bula4

¹Department of Pharmaceutical Sciences, Madras Medical College, Chennai .

²Department of Biotechnology, Loyola College, Chennai .

³Astagiri Herbal Research Foundation, Chennai .

4Rovers College of Arts and Science, Tamil Nadu .

Abstract: Alcohol and aqueous extract of Pisonia grandis (leaf) was taken and analyzed for anti-inflammatory activity. Preliminary phytochemical screening was performed for both the extracts. In the present study alcohol extract showed significant anti-inflammatory activity in carrageenan induced paw edema rats. Phytochemical analysis of alcohol extract revealed the presence of flavanoids, steroids, furan, alkaloids, anthraquinone, tannins and saponins but negative result was observed in aqueous extract except tannins. This study showed vital information regarding pharmacological and phytochemical activities of P. grandis.

Keywords: Acute toxicity; anti-inflammatory;  diclofenac sodium; Pisonia grandis

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