Studies on the Anti-Inflammatory and Antipyretic Properties of Haldinia cordifolia
Y. Ravi Kiran*, C. Manjunath, U. Ashok kumar and Y. BrahmaiahDepartment of Pharmacology, Bharathi College of Pharmacy, Bharathi Nagara, Mandya Dist, Karnataka - 571 422 India.
Abstract: The purpose of this investigation was study to the anti-inflammatory and anti-pyretic properties of stem bark extract of Haldinia cordifolia in rats. The ethanolic extract of dried stem bark of Haldinia cordifolia was investigated for anti-inflammatory (carragenan induced rat paw oedema) and anti-pyretic (brewer’s yeast induced pyrexia) activities. Pre treatment with the extract (200 - 400 mg/kg, p.o.) significantly prevented increase in volume of paw oedema in dose dependent manner. Its effects on antipyretic activity were also significant and reduce fever at higher doses. In conclusion, this study has established the anti-inflammatory activity and antipyretic activity of Haldinia cordifolia and thus justifies the ethnic uses of the plant.
Keywords: Anti-inflammatory activity; Ayurvedic; Haldinia cordifolia Back to TOC