Comparative Evaluation of Electrolytes, Glucose, Protein, Creatinine, Urea and Oxidative Stress in Male Acute Renal Failure
D. S. Baghel¹, Meena Verma¹, B. K. Agrawal², Sangeeta Paneri¹, A. K. Mathur³ and Dipendra Sharma¹¹Department of Medical Biochemistry, M. G. M. Medical College, Indore India. ²Department of Medical Biochemistry, Gandhi Medical College, Bhopal India. ³Department of Medical Biochemistry, Govt. Medical College, Sagar India.
Abstract: Acute renal failure is characterized by an abrupt decline in renal function resulting in an inability to excrete metabolic wastes and maintain proper fluid and electrolyte balance. The present study was undertaken to evaluate the serum electrolytes, glucose, protein, creatinine, urea, antioxidant enzymes and oxidant products in male acute renal failure patients. For the present study, 46 subjects of male acute renal failure aged 30 – 80 in year and 60 ages matched male healthy control were assessed. A Significant (P<0.001) increase serum potassium, creatinine, urea, and plasma malondialdehyde levels were found in male acute renal failure group while serum sodium, protein, and antioxidant enzymes were found to be decreased significantly (P<0.001) when compared to male healthy control group. This review will also discuss diagnostic tools, strategies for improved design of clinical trials, and other therapeutic interventions that will be needed to properly treat acute renal failure in the 21st century.
Keywords: Acute renal failure; Serum electrolytes; superoxide Back to TOC