Obesity and Bariatric Surgery: Ultimate Need for Vitamin D Supplementation
Saeed Ali Alsareii1, Abdulhadi Mohamed Elbashir1 and Mohammed Helmy Faris Shalayel21Surgery, College of Medicine, Najran University – Saudi Arabia.
2Biochemistry and Dermatovenereologist, Nile College – Sudan and College of Medicine, Najran University – Saudi Arabia.
Corresponding Author E-mail: drmhfs@hotmail.com
Abstract: Obesity and morbid obesity comprise mounting serious health problems reaching epidemic ratios in many countries. The cause of low levels of serum 25-hydroxyvitamin D in obese individuals remains obscure although increasing number of the postulations including vitamin D sequestration in fat tissues, rendering it less bioavailable for transformation into calcitriol, and diminished sun exposure. Bariatric surgery is one of the most efficacious long-term weight reduction procedures. Patients who are submitted to bariatric surgery are at increased risk of vitamin D insufficiency (VDI) and deficiency (VDD) that are potentially correlated with skeletal and non-skeletal pathology. Nevertheless, there is no assent considering the favorable management for these events. The severity of vitamin D deficiency due to bariatric surgery is obviously linked to the modality of bariatric procedures implemented, weight loss rate, and the intensity of malabsorption of other micro- and macro-nutrients. According to the Clinical Practice Guidelines (CPGs) on vitamin D supplementation in bariatric surgery, high doses of vitamin D supplementations, ranging from 3,000 IU daily to 50,000 IU 1 – 3 times weekly are strongly recommended. Nevertheless, they do not fulfill criteria for applicability. Patients programmed for bariatric surgery should be motivated to follow continuous physical activity, appropriate dietary habits, and vitamin D supplementations pre- and post-operatively.
Keywords: Adipokines Bariatric surgery; Obesity; Vitamin D; 25-hydroxyvitamin D; Back to TOC