Antifungal Activity of Vitex Agnus Castus-In Vitro Study

G. Mohandass1*, K. Suguna Devi2 and Amalorpavaraj3


1Sathyabama University, Chennai, India.

2Prince Dr K. Vasudevan College of Engineering and Technology, Chennai India.

3St. Joseph’s College Autonomous, Trichy, Tamil Nadu India.

Abstract:

In the present study agnuside was isolated from Vitex agnus castus by bio-assay guided fractionation and subjected to antifungal assay. Agnuside showed potent activity against tested fungi namely E. floccosum (31.25 µg/ml), T. simii (62.5 µg/ml), C. lunata (250 µg/ml), T. rubrum (62.5µg/ml), C. albicans (125 µg/ml) and Scopulariopsis sp (500 µg/ml). This study report the potency of agnuside as antifungal agent developed from plant source.

Keywords: Agnuside; antifungal; dermatophytes; MIC

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