The Emerging Role of MicroRNA21 in Oral Cancer
Dr. N. Sangeetha Narasimhan and Dr. N. Malathi Narasimhan

1Department of Craniofacial Health Sciences, College of Dental Medicine, University of Sharjah, Sharjah,U.A.E.

2Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Sri Ramachandra University, Porur- Chennai, Tamilnadu, India.

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Abstract: Oral cancer is one among the leading causes of death in developing countries of south Asia.  A very high incidence of oral cancer in India has resulted due to the prevalence of tobacco use both in smokable and Chewable forms. Though molecular level changes that occur in the initiation and progression of oral cancer has been studied, the disease process is still poorly understood unlike other cancers. MicroRNAs are the trending name in cancer research. They are non-coding RNAs that control the genome by their complementarity and affect protein synthesis. Their role in various cancers have been well studied. This paper enlightens the role of MicroRNA21 in oral cancer.

Keywords: Biomarker; Non-Coding RNA; Squamous Cell Carcinoma

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