Antibacterial Efficacy and Minimum Inhibitory Concentrations of Medicinal Plants Against Wound Pathogens
Rekha S. R, M. Kulandhaivel and Hridhya K. V.  

Department of Microbiology, Karpagam Academy of Higher Education, Coimbatore.

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Abstract: The medicinal plants are god’s gift to cure a number of diseases among the living organisms. The aim of the present study was to evaluate the antibacterial property and Minimum Inhibitory Concentration (MIC) of Azadirachta indica, Centella asiatica, Clitoria ternatea against Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa and Klebsiella species). The ethanolic extract of these plant species was prepared and demonstrated the antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella species. It exhibits broad spectrum of inhibition against the pathogens. The Minimum inhibitory concentration was determined by two fold serial dilution methods. The Concentration of plant sample of about 551.099μg of Azadirachta indica, 681.175μg of Centella asiatica, 651.175μg of Clitoria ternatea showed good activity against Staphylococcus aureus whereas 557.462μg, 623.183μg, 6137.692μg against Pseudomonas aeruginosa and 213.344μg, 611.639μg, 480.241μg against Klebsiella sp respectively. These studies prove that the plant samples exhibit good activity against the pathogen even in low concentration and it is a good antibacterial agent against the bacteria which causes wound infection.

Keywords: Medicinal Plants; Minimum Inhibitory Concentration (MIC); Antibacterial; Klebsiella Species; Staphylococcus Aureus; Pseudomonas Aeruginosa Centella Asiatica; Clitoria Ternatea and Azadirachta Indica

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