In Silico Analysis on Docking Studies of Haemolysin Protein in Vibrio Paraheamolyticus
Arunkumar T, Archana Vasuki  K and Narendrakumar G

Department of Bioinformatics, School of Bio and Chemical Engineering, Sathyabama University, Chennai – 600045.

Corresponding Author E-mail: tarunkumart@gmail.com

Abstract: From the above results the natural plants and fruit extract containanti- bacterial properties to inhibit the action of disease caused by protein(Haemolysin) present in Vibrio species. To find the drug effectiveness and inhibit the action of disease caused by protein by natural compounds is done by ligand-receptor interactions,pharmacophore and ADMET studies. The ADMET studies were done for 10 natural compounds and 6 were satisfied. The common feature pharmacophore studies were done for 10 compounds (Poses A, B,C,D). The ligand -receptor interactionswere analysed for 60 ligands with common receptor (E,F,G,H,I,J,K,L,M,N). Molecular dynamics and simulation analysed for two natural compounds(Cyanidin) and (Bergapten).

Keywords: Vibrio paraheamolyticus; Molecular dynamics; simulation; pharmacophore; Haemolysin

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