A Gift of Mother Nature – Curcumin An Alternative Chemo-Preventive Drug
Jayalalitha Sathiyamoorthy1, Priya Durairaj1, Vidyarani Shyamsundar2, Subbiah Shanmugham3, Jagadeesan G. Mani3 and Sudhakar Natarajan1

1Department of Biotechnology Dr. M.G.R Educational and Research Institute (University) Maduravoyal, Chennai-95, India.

2Centre of Oral Cancer Prevention and Research, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education (Bharath University),Pallikaranai, Chennai-99, India.

3Centre of Surgical Oncology, Government Royapettah hospital and Kilpauk Medical College, Chennai, India.

Abstract: India is the world capital for Oral cancer. The chemo preventive actions of many natural compounds were known to our fore-fathers in prehistoric era. These natural compounds are potent, less toxic and have greater biocompatibility. Natural compounds have been extensively studied over decades for various diseases including cancers. Curcumin is one of the important natural chemo preventive drug used for various cancers. It plays very important role in apoptosis, reduction of inflammation in tumour microenvironment. In this article we tried to elucidate the action of “Curcumin” in OSCC and potentially malignant disorders. Here we highlight Curcumin can be a promising therapeutic drug.

Keywords: Curcumin; Natural compounds; Chemoprevention; OSCC

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