Diagnosis and Management of an Anaplastic Thyroid Cancer: Case Report
I. Made Pande Dwipayana1, Prima Yogi1, Siswadi Semadi1, Suma Wirawan2 and Ketut Widiana3  

1Department of Internal Medicine, Faculty of Medicine, Udayana University-Sanglah General Hospital Denpasar Bali.

2Faculty of Medicine, Udayana University Denpasar Bali.

3Department of Surgery, Faculty of Medicine, Udayana University-Sanglah General Hospital Denpasar Bali.

Corresponding Author E-mail: dwipayanapande@yahoo.com

Abstract: Female, 55 years old with a chief complaint of shortness of breath and having a lump over her neck. Chest x-ray examination showed right colli mass with the impression of invading the thoracic inlet with trachea being compressed to the left. On neck and chest MSCT scan with contrast showed enlargement in the right thyroid gland with heterogenous lobulated solid mass, well demarcated border with irregular border, crossing the midline and isthmus, compressing the trachea to the left side and causing trachea narrowing. Histopathology anatomy examination consistent with anaplastic thyroid cancer, and concluded that the patient had anaplastic thyroid cancer stage IV B. Patient underwent chemotherapy using doxorubicin 80 mg as agent of choice and was given levothyroxin 100 mcg every 24 hours. Chemoterapy was done in 6 series in total for every 21 days. Patient was stable until the fifth chemotherapy. The patient dead due to respiratory failure. Anaplastic thyroid cancer is a very rare case and has a poor prognosis.

Keywords: Thyroid; Anaplastic; Chemotherapy; Thyroid cancer

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